Development of a Rapid Process Monitoring Method for Dry-Coated Tableting Process by Using Near-Infrared Spectroscopy
نویسندگان
چکیده
منابع مشابه
Development of a rapid process monitoring method for dry-coated tableting process by using near-infrared spectroscopy.
A nondestructive transmittance near-infrared (NIR) method for detecting off-centered cores in dry-coated (DC) tablets was developed as a monitoring system in the DC tableting process. Caffeine anhydrate was used as a core active pharmaceutical ingredient (API), and DC tablets were made by the direct compression method. NIR spectra were obtained from these intact DC tablets using the transmittan...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2011
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.59.868